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Tamborra, R., et al., Uncoupling protein-2 (UCP2) induces mitochondrial proton leak and increases susceptibility of non-alcoholic steatohepatitis (NASH) liver to ischaemia-reperfusion injury
Although vaccine enhancement of disease in these models could occur through other mechanisms, such studies can directly assess the protective or enhancing properties of passive antibodies (Table 1)
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The significance of our work lies in expanding the understanding of the multifunctional nature of USP2 and its implications across an array of pathophysiological circumstances
Q: How soon do skin results show up