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doi: 10.1111/apm.12159 197 KhanM
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In a randomized controlled trial (RCT) evaluating the weight change using semaglutide, it was also found that after discontinuation of semaglutide, the patients gained weight significantly as well as a significant increase in blood pressure [17], which was a reminder that weight regain may have some adverse effects
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These include not only effects of weight loss, but also improvements in endothelial function, reductions in low-grade inflammation (evidenced by a significant decrease in high-sensitivity C-reactive protein levels), and potential plaque stabilization [73]
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