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Its the more recent anti-obesity drugs, such as semaglutide (Ozempic and Rybelsus for diabetes, Wegovy for obesity) and tirzepatide (a dual GLP-1 and GIP agonist
These include: Nausea (reported in a significant proportion of participants, particularly during dose escalation) Vomiting Diarrhoea Constipation Decreased appetite Dyspepsia These effects are broadly consistent with those observed with other GLP-1 receptor agonists and tend to be most pronounced during the initial weeks of treatment
In the analyses for PIONEER 2, 3 and 4, the results remained comparable to the base case analysis, with oral semaglutide 14 mg associated with a lower cost of control than all comparators for all four endpoints (Table 3)
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32:30S-47S
Effect of mulberry leaf extract with enriched 1-deoxynojirimycin content on postprandial glycemic control in subjects with impaired glucose metabolism
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