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A: Pramlintide requires multiple daily doses

Caution This hygroscopic material readily absorbs moisture

Acid suppression medications and metformin also reduce vitamin B12 absorption and so increase the risk of deficiency

While it is well known that enhanced insulin sensitivity and low insulin levels are associated with an improved survival, there is evidence showing that attenuation of the growth hormone/IGF-1 axis may have beneficial effects in extending lifespan in humans

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Most likely, they will not recommend the supplement unless the benefits outweigh the risks