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Israel et al., A number of studies have shown that ASA, even at low anticlotting doses, acutely acetylates cyclooxygenase-1 (Cox-1) in platelets, and chronically, it also acetylates Cox-2 leading to the generation of a powerful anti-inflammatory agent

And the beneficial effects on cardiometabolic markers, like blood pressure and cholesterol, also reversed, returning to baseline after about 1.5 years

The pen device is expected to launch by April and cost about 4,500 rupees a month, it said in a filing