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The GH spike was transient and may not translate to meaningful tissue-level effects

ORCID: Affiliation: 13 Department of Biochemistry, Institute of Chemistry, University of So Paulo, Cidade Universitria, So Paulo CEP 05508-000, SP, Brazil These authors contributed equally to this work

Blood vessels in AD exhibit structural irregularities, such as twisting and varying diameters, and may develop cerebral amyloid angiopathy (CAA), significantly contributing to BBB disruption, diminished CBF, and cognitive deficits [19, 94, 184,185,186]

management mainly consists of supportive care and discontinuation of triggers

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and Sims, H.V