GHK-Cu vs Adjacent Categories Format Topical GHK-Cu (cosmetic) What it is Copper Tripeptide-1 in serums and creams Evidence base Strongest human evidence (Leyden 2002, NEEL 2023) Typical use Daily anti-aging skincare Format Injectable GHK-Cu (research-use) What it is Reconstituted vial, SubQ injection Evidence base Mostly preclinical
For cell apoptosis evaluation, cells were co-stained with Annexin V-fluorescein isothiocyanate (FITC)/PI and assessed by flow cytometry (Becton Dickinson, Franklin Lakes, New Jersey, USA)
Do not warm the peptide above room temperature or use hot water this can degrade the compound
Providers may prescribe compounded medications based on patient needs or due to medication shortages
However, it was observed that this effect was not evident in mice with healthy endothelial surfaces (76)
Pretreatment without peptides was used as a negative control, while treatment with an anti-aging peptide, acetyl hexapeptide-8 (Wrinklend), was taken as a positive control