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Urinary changes may occur indirectly through improved blood glucose control reducing hyperglycemia-related excessive urination, increased fluid intake to manage gastrointestinal side effects, or concurrent use of other medications like SGLT2 inhibitors that do affect urination

Renal function Although previous clinical studies have revealed either no change in eGFR (i.e., liraglutide versus placebo [39]) or reduced eGFR declines (eGFR preservation) (i.e., dulaglutide versus insulin or placebo [35, 40] or liraglutide versus placebo [41]), there has been no head-to-head comparison of dulaglutide versus and liraglutide on renal outcomes

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