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Nat Genet (2015) 47:3816

The cells were then washed (five times for 2 min each) with 0.1 M sodium cacodylate buffer pH 7.4 on ice and were postfixed with 1% osmium tetroxide (EMS, 19150) in 0.1 M sodium cacodylate buffer pH 7.4 for 30 min on ice

This disadvantage may result in patients who could benefit from the product not receiving it

If irritation continues to occur, apply an over-the-counter itch cream, preferably with hydrocortisone, or discontinue use

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