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A decline in mitochondrial function in the aging population could be a possible risk factor for increased mortality in COVID-19 and PASC 176
Current estimates suggest: Approximately 900,000 people living with dementia in the UK (Alzheimer's Society) Two-thirds of these have Alzheimer's disease (approximately 600,000 people) Projected to rise to 1.6 million by 2040 as the population ages Healthcare and social care costs exceed 26 billion annually Informal caregiving burden is enormous, affecting family members' employment and wellbeing This disease burden explains why the NHS and research community continue pursuing disease-modifying treatments, despite repeated setbacks like the LIFT-AD trial failure
Additionally, it is synthesized by intestinal microflora (5)
The GHK peptide sequence occurs naturally
Zamani A, Saki F, Hatami N, Koohpeyma F
Body stores can last for two to five years or longer, which is why deficiency often develops slowly and may not become apparent for some time after dietary intake or absorption becomes inadequate
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