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If pain, range of motion, or function has not moved by week 4, the dose or delivery method needs adjusting rather than extending the same protocol blindly

Preclinical studies demonstrate a remarkable ability to accelerate healing of tendons, ligaments and muscles

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Frequency of folate deficiency 54% and 36% respectively

In the original study, FOXO4-DRI showed 11.73-fold selectivity for senescent versus non-senescent human fibroblasts