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During the Zepbound lead-in treatment period, the most frequent adverse events were nausea (35.5%), diarrhea (21.1%), constipation (20.7%) and vomiting (16.3%)
Your provider may adjust this based on your tolerance, weight, and treatment goals
B12 supplementation is common among GLP-1 users, and many compounded formulations now include B12 in the blend or tirzepatide with B12
Importantly , the therapeutic selectivity of GLP-1 agonists arises from their specific receptor binding profile, which distinguishes them from other incretin-based therapies
Curr Treat Options Psychiatry
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