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Nonetheless, insulin/IGF signaling has been demonstrated to attenuate inflammatory responses, e.g., in human myocardial infarction [21] and severe thermal trauma [22] as well as in many mouse models, such as colitis [23], vascular inflammation [24], IL-1-induced cartilage degradation [25], lipopolysaccharide-provoked brain injuries [26], and experimental multiple sclerosis and autoimmune diabetes [27, 28]

Wang, X., Yang, X., Wang, Q., & Meng, D

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Molecular and cellular mechanisms involved in Helicobacter pylori-induced inflammation and oxidative stress

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Comparison of new glucose-lowering drugs on the risk of pancreatitis in type 2 diabetes: a network meta-analysis