semaglutide cause gas How to Manage (or Prevent) Side Effects | Internal Medicine & Family Medicine located in Toluca Lake, CA GLP-1 Gut Side Effects: Bloating

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More serious but less common adverse effects require clinical vigilance: Pancreatitis : Patients should be counselled to stop the medication and seek immediate medical attention if they experience severe, persistent abdominal pain radiating to the back [1] [5] Gallbladder disease : Rapid weight loss associated with GLP-1 therapy may increase cholelithiasis risk [1] Hypoglycaemia : Particularly when used alongside insulin or sulphonylureas in diabetes management Diabetic retinopathy : Semaglutide requires caution in patients with pre-existing retinopathy, who should be monitored regularly [1] Renal impairment : Dehydration from gastrointestinal side effects may affect kidney function Specific considerations for individuals with eating disorders include the potential for GLP-1 medications to exacerbate restrictive eating patterns or mask hunger cues in vulnerable individuals

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2 Substance evaluation cases agreed in advance (written procedure) MSC had already agreed several draft decisions under written procedure, including the following substances: Bis(2-propylheptyl) phthalate (EC 258-469-4) 1-(5,6,7,8-tetrahydro-3,5,5,6,8,8-hexamethyl-2-naphthyl)ethan-1-one (EC 216-133-4) 2-Propenoic acid, methyl ester, reaction products with mixed O,O-bis(branched and linear pentyl and iso-Bu) phosphorodithioates (EC 300-340-2) 4,4'-isopropylidenebis[2-allylphenol] (EC 217-121-1) 3 Dossier evaluation decisions also progressed Under dossier evaluation, MSC agreed cases including: Amines, C36-alkylenedi- (EC 273-282-8) Pivalic acid (EC 200-922-5) (Plus one compliance check case listed as confidential.) 4 Ad hoc Working Group established on SVHC ELoC cases (Art

[2] It may also cause a temporary increase in blood pressure and decrease in heart rate after each dose, and darkening of the gums, face, and breasts