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It is designed to work locally within the GI tract, which is why the oral route is the appropriate delivery method for gut-specific indications
10.1016/j.jpsychires.2006.07.013 J Psychiatr Res
At that point, decisions about adjunctive therapy (if any) are based on individual response data, not assumption
Cytosolic and mitochondrial pools are functionally compartmentalized, and exchange between these domains occurs indirectly through metabolite shuttles [110]
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Weight-loss progress, appetite changes, body composition, metabolic health, and side effects vary from person to person
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