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Acetylcarnitine also has potential regulatory effects on pain perception and emotion regulation by increasing the level of acetylated H3K27 bound to the Grm2 promoter through the epigenetic regulation of the type 2 metabotropic glutamate (mGlu2) receptor, as well as the acetylation of the NF-B p65 subunit by increasing the transcription of the Grm2 gene [40, 41]

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Moreover, a higher BMI at the start of the study was linked to a greater decline in cognitive function during the follow-up period, specifically in word-list learning

Nutrition (Burbank, Los Angeles County, Calif)