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The proportion of subjects with the GSTM1 -null genotype in the control group (43.5%) is in agreement with the literature data, where similar frequencies of this proportion were reported in case-controlled studies in Brazil [15][16] (45.7% and 41.3%, respectively) and in Europe [17] (46.9%)

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BPC-157 demonstrates exceptional safety in animal toxicology studies, with comprehensive evaluations in mice, rats, rabbits, and dogs failing to establish a lethal dose (LD) across wide dose ranges extending from standard research doses (6 g/kg) to levels exceeding 1000-fold higher concentrations (20 mg/kg), with no evidence of acute toxicity, organ-specific damage, or systemic adverse effects even following repeated high-dose administration

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Use of nonradioactive 2-deoxyglucose to study compartmentation of brain glucose metabolism and rapid regional changes in rate

N-acetylcysteine in handgrip exercise: plasma thiols and adverse reactions