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Table 1 Efficacy of GLP-1 agonists efficacy (adapted from UpToDate) (44)

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Not directly, but weight loss, whether from GLP-1 medications including Wegovy, Zepbound, and their compounded forms (such as compounded semaglutide or compounded tirzepatide) or otherwise, particularly when rapid, can lead to muscle breakdown if youre not supporting your body with enough protein, amino acids, and resistance exercise