tirzepatide going off market FDA says this weight loss drug shortage is over, but patients worry about cost and availability Tirzepatide (Zepbound, Mounjaro): Weight Loss,

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Semaglutide mimics the hormone glucagon-like peptide by sticking together amino acids to trick the body into feeling full, resulting in weight loss benefits

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The primary competitive concern is whether its modest incremental weight loss advantage over tirzepatide (the current standard) justifies its differentiated side effect profile, particularly if glucagon agonism increases bone turnover, hepatic glucose production at higher doses, or cardiovascular risk

Interestingly, GLP-1 receptor agonists, a class of drugs that includes Tirzepatide, have been found to cross the blood-brain barrier, where they may exert protective effects on neurons