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It has been suggested that these entities share with BIN, DPN, and PEM the existence of a spectrum within the spectrum (43), namely: a set of atypical histopathological features which can be variously combined with each other, thereby bearing a spectrum of lesions with increasing risk of disease progression up to overtly malignant neoplasms

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Interestingly, glutathione helps "recharge" Vitamin C after it has neutralized a free radical