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Eric Verdin, in a review published in Science (2015), documented NAD+ depletion across aging tissues and its downstream effects on sirtuin enzyme activity, PARP-mediated DNA repair, and mitochondrial function

Stenkula KG, Erlanson-Albertsson C (2018) Adipose cell size: importance in health and disease

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Tyrosine 65 is photolabeled by 8-azidoadenine and 8-azidoadenosine at the NAD binding [PMID: 1990001] Laboratory literature summary: Tyrosine 65 is photolabeled by 8-azidoadenine and 8-azidoadenosine at the NAD binding site of diphtheria toxin

After reconstitution, the solution requires refrigeration at 28 C, protected from light

Widespread alterations of -synuclein in multiple system atrophy