Results GSH depletion induces cell death in RPE cells To evaluate the effect of GSH depletion on the RPE cells, we used three different approaches: depletion of Cys 2 from cell culture media, treatment with buthionine sulphoximine (BSO, 1000 M) to block de novo synthesis of GSH, or treatment with erastin (10 M), an inhibitor of system x c 1
Metabolism: clinical and experimental , 46 (1), 8996
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These changes consisted of the individual following a polymeal diet (a diet aimed at reducing cardiovascular disease risk) that focused on nutrient-dense foods such as high quality animal products (lean meats, omega-3-rich eggs), as well as vegetables and nuts
Listening to Your Body: Recognizing Signs Your body provides valuable clues about its glutathione levels
Correlation of ferritin and GPx4 levels The Table 3