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Although Luxturna is approved for use in correcting RPE65 -induced retinal degeneration, only 12% of RP patients and 616% of Leber congenital amaurosis (LCA) patients have mutations that are treatable using this approach [36, 37]

doi: 10.1016/j.atherosclerosis.2017.04.001 131 PoulterNRPrabhakaranDCaulfieldM

Given the growing evidence that heavy metal exposure may cause various metabolic diseases partly due to heavy metal induced dysbiosis of the gut microbiota ( Oryzias melastigma )

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