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Critically, the peptide showed therapeutic efficacy even when administered after neurotoxin exposure
These agonists also play a vital role in nerve cell differentiation and inhibition of neuroinflammation
Specifications Other Known Titles: Forkhead box protein O4, Proxofim, FOXO4a, AFX, AFX1, MLLT7 Sequence: H-D-Leu-D-Thr-D-Leu-D-Arg-D-Lys-D-Glu-D-Pro-D-Ala-D-Ser-D-Glu-D-Ile-D-Ala-D-Gln-D-Ser-D-Ile-D-Leu-D-Glu-D-Ala-D-Tyr-D-Ser-D-Gln-D-Asn-D-Gly-D-Trp-D-Ala-D-Asn-D-Arg-D-Arg-D-Ser-D-Gly-D-Gly-D-Lys-D-Arg-D-Pro-D-Pro-D-Pro-D-Arg-D-Arg-D-Arg-D-Gln-D-Arg-D-Arg-D-Lys-D-Lys-D-Arg-D-Gly-OH Molecular Formula: C 228 H 388 N 86 O 64 Molecular Weight: 5358.05 g/mol FOXO4-DRI Research DRI peptides are synthetic variants of their natural counterparts
Peptide sequence: trans-3-hexenoyl-Tyr-Ala-Asp-Ala-Ile-Phe-Thr-Asn-Ser-Tyr-Arg-Lys-Val-Leu-Gly-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Met-Ser-Arg-Gln-Gln-Gly-Glu-Ser-Asn-Gln-Glu-Arg-Gly-Ala-Arg-Ala-Arg-Leu-NH Chemical details include: Molecular formula: CHNOS Molecular weight: ~5135.785136 Da Key modification: N-terminal trans-3-hexenoyl group CAS number: 218949-78-1 This structure preserves full GHRH bioactivity and extends the half-life in experimental systems
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