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[27] The connection between GSTP inhibition of the pro-apoptotic JNK pathway and the isozyme's overexpression in drug-resistant tumor cells may itself account for the tumor cells' ability to escape apoptosis mediated by drugs that are not substrates of GSTP

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In addition, mRNA of GPx3 has been detected in bovine oocytes [16] and murine blastocysts [17]