It has been widely used in anti-aging and cosmetic products in humans for decades without any adverse effects, and can be easily incorporated in creams, liposomes, dermal patches or delivered through microneedles
A patient came to my office recently and told me she had stopped her statin
(PubMed) Zannolli R, Micheli V, Mazzei MA, et al
The formula contains Ascorbic Acid, 3-O-Ethyl Ascorbic Acid, and Ascorbyl Glucoside, three forms of vitamin C that together help give the skin a clearer appearance, improve radiance, and protect against free radicals
thus, there is no absorption of B12
Proc Natl Acad Sci USA 115(48):1217612181 Vadas O, Burke JE, Zhang X, Berndt A, Williams RL (2011) Structural basis for activation and inhibition of class I phosphoinositide 3-kinases