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Regulat Peptides (2006) 134:14957

The 3-methylcrotonyl-CoA is the product of isovaleryl-CoA dehydrogenase which catalyzes the previous reaction in leucine catabolism

95% CI, 0.55-0.94

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In the current analysis in people with MASLD, fasting triglycerides were reduced by greater than 40% by retatrutide 8 mg and 12 mg doses after 48 weeks, and these reductions were significantly associated with reduced liver fat