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Further isotope labeling experiments confirmed that upon GGCT overexpression, Gln is preferentially shunted to the GSH synthesis pathway, with a significantly reduced proportion entering the TCA cycle
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Exceptions like BPC-157 and 5-Amino-1MQ have specific formulations designed for oral stability
doi: 10.1111/psyp.13694
Taken together, these findings suggest that glutathione synthesis within TLS may be distinctly regulated, with dendritic cells and fibroblasts that express the cystine/glutamate transporter playing an important role
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