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6 Mutations in several tumor suppressor genes, including APC, VHL, and RB1, are largely nonsense mutations or deletions, which reduce the expression of proteins

It has demonstrated activity against leukemia and various solid tumors and is currently under clinical investigation

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GSH protects transplanted fat grafts against ferroptosis We examined the levels of ferroptosis in the transplanted fat grafts by immunofluorescence and observed a stronger positive staining for the anti-ferroptosis markers GPX4 and SLC7A11 in the GSH-treated group than in the control group (Fig

To accommodate a possible 10% dropout rate, the final sample size was increased to 46 patients, randomly allocated in equal numbers to two parallel groups

doi:10.3390/biomedicines9111547 Vasireddi N, Hahamyan H, Salata MJ, et al