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Animal Model and Ethics Statement Wistar rats from the breeding colony at the Universidade do Extremo Sul Catarinense (UNESC), Brazil, were housed four times per cage under controlled conditions of temperature (22 1 C), relative humidity (4555%) and light-dark cycle (12:12 p.m., light on at 6 a.m.)
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Pharmacokinetic studies in rats and beagle dogs reveal that BPC-157 exhibits linear pharmacokinetic characteristics across all tested doses
Grx gene silencing in hepatocytes further sensitized hepatocytes to TNF-mediated killing
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