Frequency changes across the cycle, not the dose size
China has now approved GLP-1 therapies from Eli Lilly (Mounjaro), Innovent Biologics (mazdutide), and Guangzhou Innogen (efsubaglutide alfa), in addition to Xianyida
45 (Suppl): S19S26
Following the SUSTAIN-6 findings, the Ozempic Summary of Product Characteristics (SmPC) and specialist ophthalmology guidance emphasise the importance of: Assessing retinopathy status before initiating semaglutide Ensuring patients are up-to-date with diabetic eye screening Considering the rate of anticipated glycaemic improvement More frequent monitoring in high-risk individuals The consensus among UK diabetes specialists is that semaglutide remains an important therapeutic option, but prescribers should exercise particular caution in patients with established retinopathy and poor baseline glycaemic control
The retatrutide comparison data and availability information provide more context on this emerging treatment
Kaur G, Gupta V, Singhal R, Rawal R, Bansal P (2020b) Isolation of catechins from Roscoea purpurea