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1 Original Procognitive Characterization McCoy et al., Journal of Pharmacology and Experimental Therapeutics (2013) This paper has been under Expression of Concern since 2021 (see disclosure block above)

This represents the lower end of the standard dose range and accounts for the theoretically reduced, though likely modest, contribution of hepatic clearance

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MEK and TAK1 contain the conserved cysteine residue corresponding to ERK2 (95)

Al termine dello studio non vennero rilevate differenze nel tasso di filtrazione glomerulare (GFR), cio la quantit di sangue che i reni filtrano al minuto, creatinina, urea, elettroliti, proteinuria e albuminuria