Why the Tirzepatide vs Semaglutide Comparison Matters Both medications work on the same general territory: appetite regulation, glucose control, and body weight
The combination can significantly reduce appetite and caloric intake, which, if not carefully managed, may lead to dehydration, fatigue, or low blood pressure particularly in individuals also taking antihypertensive medications
Jun 2023;53(6):353-368.doi:10.2519/jospt.2023.11833
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We find that a licensed GLP-1 receptor agonist modulates epigenetic biomarkers of aging, positioning semaglutide as a candidate gerotherapeutic and laying the groundwork for prospectively powered, mechanism-focused trials aimed at extending healthspan in populations vulnerable to accelerated aging