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Metamucil is a fiber supplement made from psyllium husk, a compound derived from the seeds of Plantago ovata , also known as blond plantain

It not only worsens hallmark IBS symptomslike constipation, diarrhea, cramping, and abdominal painbut it is also tied to higher rates of anxiety, depression, and reduced quality of life in IBS patients 6 7

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At elevated temperatures, it accelerates dramatically

doi:10.1093/toxsci/kfn107 Bridges CC, Joshee L, Zalups RK (2011) MRP2 and the handling of mercuric ions in rats exposed acutely to inorganic and organic species of mercury

Some patients use semaglutide long-term as a chronic weight management tool, similar to blood pressure or diabetes medications