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Normality was assessed using the Shapiro-Wilk test unless a sample size was large enough to use the DAgostino & Pearson test, as per the recommendation of Graphpad Statistics Guide

This protein was originally identified as a secreted protein found in the blood at elevated levels following gastric bypass surgery, specifically vertical sleeve gastrectomy (VSG)

7 Loss of SLC25A39/40 decreases the steady state levels of iron-sulfur containing proteins and phenocopies iron-sulfur cluster deficiency