Furthermore, glucose or lipid starvation can lead to activation of AMP-activated protein kinase (AMPK), a major cellular energy sensor, which is found to be active in motor neurons of ALS patients and its activity correlates to the cytoplasmic mislocalization of TDP-43
53 (Suppl 1): 3740
Curi TC, De Melo MP, De Azevedo RB, Zorn TM, Curi R
J Bioenerg Biomembr 48:591598 Demarest TG, Schuh RA, Waddell J, McKenna MC, Fiskum G (2016) Sex-dependent mitochondrial respiratory impairment and oxidative stress in a rat model of neonatal hypoxic-ischemic encephalopathy
In the liver, the detoxification process relies on glutathione S-transferase (GST) and GSH, a mechanism crucial for clearing harmful substances from the body
(2011) Exercise, protein metabolism, and muscle growth Yoshida T, Delafontaine P