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[8, 9] Thats because it increases growth factors like VEGF and FGF while building the new blood vessels that bring much-needed nutrients to injured tissues

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Long-Term Medication Users Medications such as metformin (used for diabetes) and proton pump inhibitors (used for acid reflux) can interfere with B12 absorption when taken long term, making supplementation necessary

Biochemical assays show increased glycerol release, reflecting enhanced lipolysis, alongside reductions in intracellular lipid accumulation

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Who really benefits B12 shots make the biggest difference for people who are genuinely low, including: People with a diagnosed B12 deficiency Vegans and vegetarians, since B12 comes mainly from animal foods Older adults, who absorb B12 less efficiently People with pernicious anemia or digestive conditions that block absorption How to use B12 shots the right way If you decide B12 shots fit your plan, treat them as one piece of a bigger picture: Build the plan on food