There's no evidence saying these drugs cause C cell hyperplasia in humans, so the FDA gave it a black box warning until we know more
Psychiatry 10, 238
[29] In 1982, they published their discovery that the gene for proglucagon actually codes for three peptides, namely glucagon and two novel peptides
During this phase, track your bowel movements, any bloating or gas, and hydration
Note that semaglutide and tirzepatide typically have different standard dosing levels, which is handled in the regression model by the drugType:dose interaction term
By Lana Pine | Published on August 2, 2026 1 min read GLP-1 medications have gone from a diabetes treatment most people had never heard of to one of the most talked-about drug classes in modern medicine, all in the span of a few years