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Effects of weight change on taste function
Charts what moved, what didn't
The Jastreboff Phase 2 trial randomised 338 adults with body mass index 30 (or 27 with at least one weight-related condition) to retatrutide 1, 4, 8, or 12 mg subcutaneously once weekly, or placebo, for 48 weeks
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Some are approved for type 2 diabetes
Short peptides often enter tissues more readily, producing local changes without strong systemic hormone shifts
