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Minerva Chir 1990
Long-term HFD consumption reduced hepatic expression of glutaredoxins The de-glutathionylation of protein-mixed disulfides is primarily catalyzed by glutaredoxins (Grxs) 31
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In line, Grx2 knockout mice resemble phenotypes of mice expressing a hypomorphic Gpx4 allele, such as lipid peroxidation in the brain or loss of parvalbumin-positive neurons [71]
23 Nowadays, there is no report on the possible involvement of GSTP1 in the regulation of liver regeneration although the crucial role of JNK pathway in the entry into and progression through G1 phase of the cell cycle in hepatocyte is well established
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