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Hydroxocobalamin is the preferred agent in this patient population (see separate monograph in Less Common Drugs)

Oral cyanocobalamin supplementation (typically 50150 micrograms daily) represents an appropriate option for patients with dietary deficiency without intrinsic factor deficiency or malabsorption issues

It is an even bigger problem if the skin is oily

Epigenetic mechanisms including DNA and histone modifications, as well as regulation by non-coding RNAs have pivotal roles in different stages of neurogenesis

Glycine carrier: reserved for patients with B-12 sensitivity, methylation issues, or histamine reactions

But its better safe to avoid these drugs in the above mentioned periods