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Quinlan et al., 2013), complex I and complex III (Venditti et al., 2013) have been shown to be the most important sources of mitochondrial superoxide generation, although significant production of ROS in complex II has recently also been reported (Quinlan et al., 2012)

Discontinuing the protocol because of manageable discomfort means losing the cumulative biological benefits that GHK-Cu builds over weeks and months of consistent use

10.1016/j.phymed.2025.157030 Summary Keywords 5-aminosalicylic acid, combination therapy, naturalbioactive compounds, synergistic effect, traditional Chinese medicine, ulcerative colitis Citation Dong W, Wu H, Liu T and He W (2026) Advancing ulcerative colitis therapy: a review of 5-ASA synergy with traditional Chinese medicine and natural bioactive compounds

Metabolome measurements were carried out through a facility service at Human Metabolome Technologies Inc., Tsuruoka, Japan

Vitamin B12 is available in different forms, including tablets, sprays, and injections