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Yet these same pathways create problems elsewhere

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Foundational mouse study (Baar et al., 2017, Cell) Designed FOXO4-DRI and showed selective senescent-cell clearance, with restored fitness, fur density, and kidney function in aged and chemotherapy-treated mice

doi:10.1016/j.freeradbiomed.2008.10.040 Tsai CC, Chen HS, Chen SL, Ho YP, Ho KY, Wu YM, Hung CC (2005) Lipid peroxidation: a possible role in the induction and progression of chronic periodontitis

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Cravings, emotional eating patterns, and reward-driven food behaviors gradually diminish