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GLP-1 class medications caused thyroid tumors in rodent studies, but this has not been confirmed in humans

10.1136/bmj.n71 49 PageM

Discontinuation Rates Treatment Discontinuation Due to Adverse Events: Retatrutide 9mg: 12.2% Retatrutide 12mg: 18.2% Placebo: 4.0% Interestingly, some discontinuations were attributed to "perceived excessive weight loss" participants felt they were losing weight too rapidly or had reached their desired weight and chose to discontinue

It is believed to be accurate at the time of posting and is subject to change

For the experimental group, participants had to be on a maintenance dose (at least 4 weeks, Supplemental Table 1) of a GLP-1RA medication for weight loss

If weight loss has felt like an uphill battle, GLP-1S compounded semaglutide may offer support that finally feels aligned with your body not working against it