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doi: 10.1002/jps.20738 36

Preclinical studies have shown that GLP-1RAs influence essential signaling pathways, including the activation of farnesoid X receptor (FXR) and liver X receptor (LXR), which are crucial in lipid metabolism and inflammation (Yan et al., 2023)

31 In OVX insulin-deficient streptozotocin (STZ) diabetic rats, liraglutide significantly lowered serum CTX-I levels and inhibited osteoclast differentiation

It concluded: "There is a strong indication that GLP-1 receptor agonists may have a useful role in future treatment of Parkinson's disease." Of note, both trials had a washout period after the drug treatment ended and the benefit for motor symptoms persisted

Dr Baxi says he refused, asking him what he would do after losing 10kg on the drug