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The Nature Scientific Reports 2016 study confirmed that GHK-Cu produced no cytotoxicity to human keratinocytes at concentrations up to 5,800 micromolar over 72 hours and did not induce inflammatory biomarkers

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HC has been identified as a safe cosmetic ingredient for topical formulations with good moisturizing properties at the stratum corneum layer of the skin

Iron oxides are generally non-toxic and non-allergenic