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Circulating L-carnitine is distributed to two kinetically defined compartments: one large and slow-turnover (presumably muscle), and another relatively small and rapid-turnover (presumably liver, kidney, and other tissues)

The mean duration of exposure to semaglutide or placebo in the study was 34.2 months

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All of these are handling notes in a research context and not a dosing recommendation

doi: 10.1016/s1473-3099(23)00551-0 410 TianJ.WangY.LuZ.SunC.ZhangM.ZhuA.et al