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Perhaps most exciting is the potential for GLP-1s to assist with addiction treatment
This gradual glucose release, in turn, leads to increased GLP-1 secretion
These medications work by mimicking the GLP-1 hormone, which helps regulate blood sugar levels and appetite
These translocate to the nucleus to induce DNA fragmentation and cell necrosis
We note that although the chondroprotective effects of metformin was clearly attenuated in Nrf2 KO mice, micro-CT analysis revealed some variability in trabecular bone parameters, including occasional increases in subchondral trabecular bone amounts in Nrf2 KO OA mice (Fig
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