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Metabolic and hormonal changes include restoration of baseline gastric emptying rates, return of pre-treatment appetite signals, and loss of the medication's insulinotropic effects

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Am J Physiol Endocrinol Metab 312:E117-e125 Bustin SA, Benes V, Garson JA, Hellemans J, Huggett J et al (2009) The MIQE guidelines: minimum information for publication of quantitative real-time PCR experiments

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The jump from 5 mg to 10 mg produced an additional 5.4% weight loss