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Without maintenance, the improvements will gradually diminish over time as natural collagen loss continues, but much of the structural rebuilding persists

That allows time to: Review healthcare claims Analyze pharmacy spending Evaluate PBM performance Compare funding arrangements Consider level-funded options Update plan design Improve employee communications Planning early creates better negotiating leverage and often leads to stronger renewal outcomes

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The Plavix cliff also illustrated the paragraph IV lottery dynamic: generic companies that successfully challenge a patent before expiry can be rewarded with 180-day exclusivity the period during which only they and the innovator (via AG) can sell the drug

Possible side effects include mild bloating, stomach upset, or allergic reactions